ACS Combinatorial Science p. 516 - 521 (2019)
Update date:2022-09-26
Topics:
Majnooni, Sahar
Duffield, Joseph
Price, Jessica
Khosropour, Ahmad Reza
Zali-Boeini, Hassan
Beyzavi, M. Hassan
Several straightforward and practical processes have been established for the construction of 2-aminothiazoles, 1,3-thiazoles and 1,3-selenazoles from aryliodoazides. These strategies successfully proceed with a wide spectrum of substituted thioamides and its derivatives producing the resulting five-membered heterocycles obtained in satisfactory yields. The unique features of these protocols are operational simplicity and highly functional group tolerance, which make them convenient and practical routes for the preparation of various libraries of 2-aminothiazoles, 1,3-thiazoles, and 1,3-selenazoles.
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