A Bridged Tetrahydrophosphole Ylide Derived from 9-Phenylphosphabicyclononane: A Reagent for E-Selective Wittig Reactions

DOI: 10.1021/jo00060a001

Source and publish data:

Journal of Organic Chemistry p. 1985 - 1986 (1993)

Update date:2022-07-30

Topics:

Authors:

Vedejs, E.

Peterson, M. J.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00060a001

The bicyclic ylide 4 reacts with aldehydes to afford the E-alkenes.Selectivity is 94 - 6percent E for unbranched aldehydes, but the selectivity decreases with increasing α-branching.Ylide 4 is the first E-selective, nonstabilized ylide that allows efficient utilization of the P-alkyl substituent.

Full text of DOI:10.1021/jo00060a001

Products guided by the article

Product name:9-phenyl-9-phosphabicyclo[4.2.1]nonane oxide

Cas No:40468-93-7

R&D Labs maybe for 40468-93-7

Sigma-Aldrich Chemie GmbH

website:http://www.sigmaaldrich.com

Contact:800 558-9160

Address:Industriestrasse 25CH-9471 Buchs SGSwitzerland
Jinzhou Jiutai Pharmaceutical Co.,Ltd

Contact:+86-0416-5179890

Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
Beijing ZhongDaXinHe Chemical Product Co.,Ltd(expird)

Contact:010-52876516

Address:tongzhoubeiyuan
Shandong Topscience Biotech Co., Ltd.

Contact:0633-2619278

Address:No. 98 Lanshan West Road, Lanshan District, Rizhao, Shandong Province, P.R. of China
Wuhan Chemwish Technology Co., Ltd

website:http://www.chemwish.com/

Contact:+86-27-67849912

Address:Room 1311, Unit 2, Block1, Innovation Road East Lake High-tech Development Zone Wuhan, Hubei，P.R. China

Relevant to this article

Six-coordinate and five-coordinate Fe^II(CN)₂(CO)_x thiolate complexes (x = 1, 2): Synthetic advances for iron sites of [NiFe] hydrogenases

Doi:10.1021/ja011504f
(2002)
Binuclear Co(II)Co(II), Co(II)Co(III) and Co(III)Co(III) complexes of "short" salen homologues derived from the condensation of salicylaldehyde and methanediamine or phenylmethanediamines. Synthesis, structures and magnetism

Doi:10.1039/b105594c
(2001)
Optimization of CRF₁R binding affinity of 2-(2,4,6- trichlorophenyl)-4-trifluoromethyl-5-aminomethylthiazoles through rapid and selective parallel synthesis

Doi:10.1016/j.bmcl.2004.10.055
(2005)
Doi:10.1246/bcsj.43.1782
(1970)
Electrophilic attack of [I(py)₂]⁺(NO₃^-) on three-coordinate Pt⁰ precursors: Synthesis and in vitro antitumor activity of water-soluble, five- coordinate Pt(II) complexes

Doi:10.1002/1099-0682(200008)2000:8<1717::aid-ejic1717>3.0.co;2-1
(2000)
In silico studies, synthesis and pharmacological evaluation to explore multi-targeted approach for imidazole analogues as potential cholinesterase inhibitors with neuroprotective role for Alzheimer's disease

Doi:10.1016/j.bmc.2018.01.029
(2018)

Article Doi