Journal of Medicinal Chemistry p. 1459 - 1465 (1982)
Update date:2022-07-29
Topics:
Gueremy, Claude
Audiau, Francois
Uzan, Andre
Fur, Gerard Le
Leger, Jean-Michel
Carpy, Alain
A series of 30 6-chloro-2,4-diaminopyrimidines was synthesized and tested in vitro as inhibitors of <3H>spiroperidol binding.The affinity for the dopamine receptor was shown to be related to the 6-chloro-4(N-methylpiperazine)pyrimidine structure bearing a
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