Tetrahedron Letters p. 2295 - 2298 (1999)
Update date:2022-08-04
Topics:
Dube, Daniel
Scholte, Andrew A.
A one pot selective mono N-alkylation of primary amides, thioamides, carbamates and ureas has been developed using aromatic and aliphatic aldehydes as alkylating agents and trifluoroacetic acid / triethylsilane as reagents. Application to an efficient synthesis of a primary amine from the corresponding aldehyde via the carbamate intermediate is presented.
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Doi:10.1039/CT9222101863
()Doi:10.1002/anie.201305584
()Doi:10.1246/cl.2002.708
(2002)Doi:10.1055/s-2002-33118
(2002)Doi:10.1023/A:1014557226260
(2001)Doi:10.1248/cpb.50.656
(2002)
