Intramolecular triple heck reaction. An efficient entry to fused tetracycles with a benzene core

Article abstract of DOI:10.1021/jo0258094

Twelve examples of 1,3,5-tribromo-2,4,6-trienylbenzenes were easily synthesized by alkylation, etherification, and amination methods. Under conditions A and B, a series of tetracycles with a benzene core, i.e., fused 5,6,6-, 6,6,6-, and 6,6,7-tetracyclic compounds, were prepared efficiently via this intramolecular triple Heck reaction protocol.