A chemoenzymatic approach towards moenomycin structural analogues

DOI: 10.1016/S0040-4020(96)01116-7

Source and publish data:

Tetrahedron p. 1695 - 1706 (1997)

Update date:2022-08-04

Topics:

Authors:

Range, Gerhard

Kraehmer, Ralf

Welzel, Peter

Mueller, Dietrich

Herrmann, Guido F.

Kragl, Udo

Wandrey, Christian

Markus, Astrid

Van Heijenoort, Yveline

Van Heijenoort, Jean

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Article abstract of DOI:10.1016/S0040-4020(96)01116-7

The trisaccharide moenomycin analogue 1c has been synthesized. One starting material was N-acetyllactosamine obtained by an enzyme-catalyzed transglycosylation. 1c differs from moenomycin degradation product 1a only in two positions of unit C. In contrast to 1a the synthetic 1c is antibiotically inactive.

Full text of DOI:10.1016/S0040-4020(96)01116-7

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