EVIDENCE FOR A REVERSIBLE d,?*-COMPLEXATION, β-CUPRATION SEQUENCE IN THE CONJUGATE ADDITION REACTION OF GILMAN REAGENTS WITH α,β-ENONES.

Article abstract of DOI:10.1016/S0040-4039(00)95113-X

In situ trapping of reaction intermediates combined with stereochemical studies of the reaction of lithium dimethylcuprate with enones provides evidence for a pathway involving d,?^*-cuprate-enone and copper(III) β-adducts as important intermediates in cuprate-mediated conjugate addition of carbon.