Synthesis and biological evaluation of substituted benzenesulfonamides as novel potent membrane-bound phospholipase A2 inhibitors

DOI: 10.1021/jm00111a048

Source and publish data:

Journal of Medicinal Chemistry p. 2260 - 2267 (1991)

Update date:2022-09-26

Topics:

Authors:

Oinuma Oinuma

Takamura

Hasegawa

Nomoto Nomoto

Naitoh Naitoh

Daiku Daiku

Hamano Hamano

Kakisawa

Minami Minami

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Article abstract of DOI:10.1021/jm00111a048

A novel series of 4-[N-methyl-N-[(E)-3-[4-(methylsulfonyl)phenyl]-2-propenoyl]amino]benz enesulfonamides has been prepared and evaluated as membrane-bound phospholipase A₂ inhibitors. A structure-activity relationship study indicated that the o

Full text of DOI:10.1021/jm00111a048

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