
Synthetic Communications p. 4545 - 4556 (2004)
Update date:2022-08-05
Topics:
Liu, Jun
Liu, Qun
Yu, Haifeng
Ouyang, Yan
Dong, Dewen
2-[1,3]Dithian/dithiolan-2-ylidene-3-oxo-butanamide 2a/2b were synthesized and investigated in the thioacetalization reaction of aldehydes/ketones 3. The experiments revealed that 2a could be used as a nonthiolic, odorless 1,3-propanedithiol equivalent in the conversion of aldehydes/ketones into the corresponding dithianes 4, however, 2b was less effective. Moreover, the chemoselectivity of the thioacetalization of 3 in the presence of 2a is discussed.
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