Synthesis and Anticonvulsant Activities of α-Heterocyclic α-Acetamido-N-benzylacetamide Derivatives

DOI: 10.1021/jm00074a016

Source and publish data:

Journal of Medicinal Chemistry p. 3350 - 3360 (1993)

Update date:2022-08-05

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Authors:

Kohn, Harold

Sawhney, Kailash N.

Bardel, Patrick

Robertson, David W.

Leander, J. David

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Article abstract of DOI:10.1021/jm00074a016

Earlier studies showed that (R,S)-α-acetamido-N-benzylacetamides (2) containing a five- and six-membered aromatic or heteroaromatic group appended at the C(α) site displayed outstanding activity in the maximal electroshock-induced seizure (MES) test in mi

Full text of DOI:10.1021/jm00074a016

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