Journal of the Chemical Society. Chemical communications p. 576 - 578 (1983)
Update date:2022-09-26
Topics:
Gani, David
Young, Douglas W.
Samples of β-alanine stereospecifically labelled with deuterium in each of the four C-H bonds have been synthesised; these have been used to show that, in the first step of uracil metabolism, the pyrimidine is reduced by dihydrouracil dehydrogenase with overall trans-addition of hydrogen at the si-face at C-6 and the si-face at C-5.
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