10.1002/adsc.201800107
Advanced Synthesis & Catalysis
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Representative method for the synthesis of
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and TBHP (70% in water) (321 µL, 5 equiv)
dissolved in 200 µL chlorobenzene and refluxed for 8
o
h at 120 C. The reaction mixture was monitored by
thin layer chromatography. The mixture was
extracted with ethyl acetate, dried over Na2SO4 and
evaporated under reduced pressure. The compound
was purified by column chromatography to give 3l
(82 mg, 78%) as a white solid.
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was added to a mixture of styrene (2e) (104 mg, 1.0
mmol), Cu(OAc)2 (18 mg, 20 mol%) and TBHP
(70% in water) (321 µL, 5 equiv) dissolved in 200 µL
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chlorobenzene and refluxed for 8h at 120 C. The
reaction mixture was monitored by thin layer
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ethyl acetate, dried over Na2SO4 and evaporated
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Acknowledgements
P.S. thanks MHRD, IIT Delhi for her graduate fellowship. The
authors thank CSIR, India (02(180)/14/EMR-II) for financially
supporting this work and DST-FIST for funding the ESI-HRMS,
and SCXRD facility at IIT Delhi.
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