Solvent free synthetic procedure throughout reaction and separation: ylide reaction with alkyl aryl ketones in the absence of solvent followed by distillation to give 1-alkyl-1-aryloxiranes

Article abstract of DOI:10.3987/COM-97-S69

After heating a mixture of trimethylsulphonium iodide, tBuOK and an alkyl aryl ketone at 60-70 °C for 1-5 h, vacuum distillation gave the corresponding 1-alkyl-1-aryloxirane. The procedure was accomplished without using any solvent throughout the reaction and the separation.