β-Elimination of the Isonitrile Group in Alkylation Reactions of C-H Acids Activated by the Isonitrile Function

DOI: 10.1039/c39820000979

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 979 - 980 (1982)

Update date:2022-08-03

Topics:

Authors:

Jawdosiuk, Mikolaj

Uminski, Maciej

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1039/c39820000979

During phase-transfer alkylation of the isonitriles R1R2CHNC with X-CH2-Y, where X is a leaving group and Y an electron withdrawing group, some of the alkylation products undergo β-elimination of the isonitrile function to yield R1R2C=CHY.

Full text of DOI:10.1039/c39820000979

View Article Online / Journal Homepage / Table of Contents for this issue

View Article Online

Products guided by the article

Product name:1-nitro-3-(2,2-diphenylethenyl)benzene

Cas No:70600-02-1

R&D Labs maybe for 70600-02-1

N&R INDUSTRIES,INC

Contact:Tel:+86-29-88764861 Fax:+86-29-88764861

Address:Rm#2107, Block A, Epin Meidao Building, Gaoxin Rd, Hi-Tech Zone, Xi’an, China
Shanghai birch chemical technology co.,ltd

Contact:+86-21-54096810

Address:No.2588,Jungong Road,Shanghai,China
Xi'an caijing Opto-Electrical Science & Technology Co., LTD

Contact:+86-29-88294447

Address:NO.168 Zhangba Rd. East, Xi'an, P.R.China
Jinzhou Jiutai Pharmaceutical Co.,Ltd

Contact:+86-0416-5179890

Address:No.41, Taianli, Taihe District, Jinzhou, Liaoning
Basilea Pharmaceutica China Ltd.

Contact:+86-513-82198075

Address:No.638 Xiushan Road(East),Haimen, Jiangsu 226100, P.R.China

Relevant to this article

Catalytic Asymmetric Total Syntheses of Naturally Occurring Amarylidaceae Alkaloids, (-)-Crinine, (-)- epi-Crinine, (-)-Oxocrinine, (+)- epi-Elwesine, (+)-Vittatine, and (+)- epi-Vittatine

Doi:10.1021/acs.orglett.8b01703
(2018)
From 1-acyl-β-lactam human cytomegalovirus protease inhibitors to 1-benzyloxycarbonylazetidines with improved antiviral activity. A straightforward approach to convert covalent to noncovalent inhibitors

Doi:10.1021/jm0492812
(2005)
Doi:10.1007/BF00911616
()
Synthesis of a novel C-10 spiro-epoxide of paclitaxel

Doi:10.1016/S0960-894X(01)00280-3
(2001)
Lipase-catalysed resolution of 2-dialkylaminomethyicyclohexanols

Doi:10.1016/S0957-4166(98)00019-6
(1998)
Synthesis of rhodium porphyrin aryls via intermolecular arene carbon-hydrogen bond activation

Doi:10.1016/s0020-1693(97)05825-8
(1998)

Article Doi