Bioorganic and Medicinal Chemistry Letters p. 3511 - 3514 (1998)
Update date:2022-08-02
Topics:
Lee, Jeewoo
Kang, Mee Kyoung
Chun, Moon Woo
Jo, Yeong Joon
Kwak, Jin Hwan
Kim, Sunghoon
A series of methionine analogues have been synthesized as inhibitors of methionyl-tRNA synthetase and evaluated for their inhibitory activities of E. coli methionyl-tRNA synthetase and bacterial growth. Among them, L-methionine hydroxamate 20 has proved to be the best inhibitor of the enzyme with K(i) = 19 μM and showed a growth inhibition against E. coli JM 109, P. vulganis 6059 and C. freundii 8090.
View MoreSinoway International (Jiangsu) Co., Ltd.
Contact:+86-25-86630167
Address:17 Beijing Road (West), Nanjing, China
Dayang Chem (Hangzhou) Co.,Ltd.
website:http://www.dycnchem.com
Contact:+86-571-88938639
Address:9/F, Unit 2 Changdi Torch Building, 259# WenSan Road, Xihu District, Hangzhou City 310012, P.R.China
WUXI KINGHAN BIO-MEDICAL&CHEMICAL INC.
Contact:13861062998
Address:Room 1316,No.1619 Huishan Avenue,Wuxi,China
Shanghai Sungo Technology Chemical Co., Ltd
Contact:0086-21-51385579
Address:Room2010, F/20, Tonghua Plaza, NO 345 Jinxiang Road, Jinqiao Export Processing Zone, Shanghai, 201206 P.R.CHINA
Jintan City Mego Chemical Co., Ltd
Contact:+86-0519-82814387
Address:23# Dengguan Town, Jintan, Jiangsu Province, China
Doi:10.1007/BF00665585
(1991)Doi:10.1016/S0040-4039(00)80366-4
(1988)Doi:10.1080/00397911.2019.1566472
(2019)Doi:10.1016/j.jorganchem.2004.02.007
(2004)Doi:10.1021/acs.joc.1c01424
(2021)Doi:10.1002/jps.2600680629
(1979)
