Heterocyclic Cation Systems. 14. Synthesis of Thienodiazepine, Thiazolodiazepine, and s-Triazolothiazolodiazepine Derivatives

Article abstract of DOI:10.1021/jo01290a010

Synthesis of hetero<1,4>diazepines is described.The synthetic route involved reactions of the anion of malononitrile or cyanamide toward 2-substituted 1,3-oxathiolium cation 1 to give amino ketone derivatives 3 and 4 as the key intermediates.Introducti