Trapping of Metabolically Generated Electrophilic Species with Cyanide Ion: Metabolism of 1-Benzylpyrrolidine

DOI: 10.1021/jm00176a006

Source and publish data:

Journal of Medicinal Chemistry p. 133 - 139 (1980)

Update date:2022-07-30

Topics:

Authors:

Ho, Bert

Castagnoli, Neal

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00176a006

Incubations of 1-benzylpyrrolidine (4) and specifically deuterium-labeled analogues of 4 with rabbit liver microsomal preparations in the presence of cyanide ion have led to the characterization of 1-benzyl-2-cyanopyrrolidine (13), cis- and trans-1-benzyl

Full text of DOI:10.1021/jm00176a006

Products guided by the article

Product name:cis-N-benzylpyrrolidine-2,5-dicarbonitrile

Cas No:72219-11-5

R&D Labs maybe for 72219-11-5

Zhuhai Biliantian Bio-Tech Co., Ltd.(expird)

Contact:0756-7716996

Address:Gongyuan Raod,Zhuhai,Guangdong Prov.China.
Chengdu NoVi Biotechnology Co., Ltd.(expird)

Contact:13551243286/028-81458053

Address:NO.168-1-224 JULONG ROAD WUHOU DISTRICT, CHENGDU CITY,SICHUAN PROVINCE
Chengdu Baishixing Science and Technology Industry Co., Ltd.

website:http://www.cd-bsx.com

Contact:+86-28-88531548

Address:#217,North of Industry Road,Heshan Town,Pujiang County,Chengdu,Sichuan,China.
ZiBO KuoDing Trade company Ltd

website:http://www.sdzbkd.com

Contact:86-13361591822

Address:GongQingTuan road
Shanghai Yuking Water Soluble Material Tech Co., Ltd

Contact:86-21-68286299

Address:4F, 13B, No. 600, South Xinyuan Road 201306, Shanghai, China

Relevant to this article

Enantioselective synthesis of indolizidine and quinolizidine derivatives from chiral non-racemic bicyclic lactams

Doi:10.1016/j.tet.2004.04.055
(2004)
Syntheses of 2,3-dicyano-5a,8a-dihydro-5a-hydroxycyclopentano[1',2':4,5]pyrrolo[2,3-b]pyra zines and 2,3-dicyanocyclohexano[1',2':4,5]pyrrolo[2,3-b]pyrazines

Doi:10.1002/jhet.5570370546
(2000)
Montmorillonite KSF, a mild and efficient catalyst for benzodioxepination of carbonyl compounds

Doi:10.1080/00397919308011246
(1993)
Highly stereoselective addition of organozinc reagents to pentopyranose derived glycals: Effect of protecting group and assignment of C-glycoside stereochemistry

Doi:10.1016/j.tet.2004.04.004
(2004)
Reduction of nitro aromatic compounds by zero-valent iron metal

Doi:10.1021/es950211h
(1996)
Acid-Catalyzed Rearrangement of α-Aminoalkylidene-β-alkoxy β-Lactams

Doi:10.1021/jo01294a004
(1980)

Article Doi