Synthesis and nucleophilic properties of 1,2 -dialkyl-3-nitropyrroles and 1,5-dialkyl-4-nitropyrrole-2-carboxylic acid derivatives

DOI: 10.1039/P19960002277

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 2277 - 2289 (1996)

Update date:2022-08-05

Topics: Synthesis nucleophilic

Authors:

Molins-Pujol, Antoni M.

Moranta, Concepcio

Arroyo, Carmina

Rodriguez, M. Teresa

Meca, M. Carmen

Pujol, M. Dolors

Bonal, Joaquim

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Article abstract of DOI:10.1039/P19960002277

1,2-Dialkyl-3-nitropyrroles 1 are versatile synthetic tools for obtaining substituted pyrrolidines or fused ring heterocycles such as pyrrolopyridines, pyrrolopyrimidines or pyrroloazepines. We have established a method for obtaining compounds related to structure 1 and studied the reactivity as a nucleophile of the benzylic type moiety in the alkyl residue bound to position 2.

Full text of DOI:10.1039/P19960002277

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