Journal of Medicinal Chemistry p. 1652 - 1661 (1989)
Update date:2022-08-05
Topics: Synthesis Experimental Renin inhibitors Scissile Bond
Allen
Fuhrer
Tuck
Wade
Wood
The synthesis of five amino phosphorus derivatives, 1a-e, is described. The derivatives were incorporated into a series (18) of analogues of the 5-14 portion of angiotensinogen, in most cases at the scissile Leu-Val bond. The resultant compounds were test
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