Journal of Medicinal Chemistry p. 462 - 465 (1980)
Update date:2022-08-05
Topics:
Wright, William B.
Greenblatt, Eugene N.
Day, Ivana P.
Quinones, Nicanor Q.
Hardy, Robert A.
Four 11-(1-piperazinyl)5H-pyrrolo<2,1-c><1,4>benzodiazepines were prepared and evaluated as central nervous system agents.All were active psychotropic agents as determined by animal screening tests.The most interesting compound, 11-(1-piperazinyl)-5H-pyrrolo<2,1-c><1,4>benzodiazepine, showed dual activity as an antidepressant against tetrabenazine depression and as a neuroleptic as measured by protection vs. amphetamine lethality in grouped mice.
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Doi:10.1002/hlca.200690058
(2006)Doi:10.1016/S0040-4039(01)95375-4
(1979)Doi:10.1021/jo00347a058
(1982)Doi:10.1021/ja00526a021
(1980)Doi:10.1016/S0040-4039(01)90921-9
(1963)Doi:10.1021/jo00287a031
(1989)
