Chemical and Pharmaceutical Bulletin p. 4914 - 4922 (1984)
Update date:2022-08-02
Topics:
Hayakawa
Suzuki
Suzuki
Tanaka
As a part of our search for new antibacterial agents, 5-ethyl-8-oxo-5,8-dihydrofuro[3,2-b][1,8]naphthyridine-7-carboxylic acid and its 2,3-dihydrofuro derivative, the 4-aza analogue of droxacin, were synthesized and their antibacterial activities were tested. Both compounds exhibited high antibacterial activities and a broad antibacterial spectrum. In an attempt to find a suitable method for industrial-scale synthesis of these compounds, several methods for the furan ring cyclization of 6,7-disubstituted 1,8-naphthyridine-3-carboxylate derivatives were compared.
View MoreWUXI HONOR SHINE CHEMICAL CO.,LTD
Contact:+86-510-83593312
Address:No.1699 Huishan avenue,Huishan district,Wuxi ,Jiangsu,China,214177.(Wuxi Huishan Ecomonic Develop Zone )
website:http://www.easchem.com
Contact:+86-731-89722861 89722891
Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.
Contact:86-574-26865651
Address:529 YuanBaoShan Road, Beilun District
Shanghai Yurui Biotechnology(Anyang) Pharmaceutical Co., Ltd
Contact:+86-0372-3662335 +86-0372-3661988
Address:hanling industrial park anyang
YanCheng LongShen Chemical Co.,Ltd.
Contact:+86-515-86668866
Address:No.13,Weiyi Road,Funing Aoyang Industrial Park
Doi:10.1021/ja00521a100
(1980)Doi:10.1002/ejoc.200400047
(2004)Doi:10.1016/j.tetlet.2014.01.024
(2014)Doi:10.1021/jo01299a041
(1980)Doi:10.1021/ja01624a036
(1955)Doi:10.1002/ardp.19793121202
(1979)
