Organocuprate-Induded Coupling of Propargyl or Enyne Alcohols Using (Methylphenylamino)tributylphosphonium Iodide. Regiocontrolled Synthesis of Allenes and Conjugated Enynes

Article abstract of DOI:10.1021/jo01310a066

Regioselective synthesis of allenes is directly achieved via organocuprate-mediated γ-coupling of propargyl alcohols by using the title reagent (1). Alternatively, the coupling between 1,4-enyn-3-ols and alkyllithium affords the conjugated Z enynes regio-