Reaction of peroxy-p-quinol acetates with trifluoroacetic anhydride. Formation of new oxepinone derivatives.

Article abstract of DOI:10.1016/S0040-4039(00)71389-X

The reaction of peroxy-p-quinol acetates derived from 4-R-2,6-di-t-butylphenols (R = Me, Et, n-Pr, s-Bu) with trifluoroacetic anhydride gives the corresponding 2-tri-fluoroacetylmethylidene-5-oxepinone derivatives. A favoured mechanism involves efficient conversion of a quinoxy cation intermediate primarily formed into an oxepinone derivative to which a trifluoroacetyl group is incorporated.