Synthesis and antiviral activity of 1-(2-deoxy-β-D-ribofuranosyl)-5-(methylmercapto)-2-pyrimidinone

DOI: 10.1021/jm00133a022

Source and publish data:

Journal of Medicinal Chemistry p. 109 - 112 (1981)

Update date:2022-08-02

Topics:

Authors:

Schroeder

Bardos Bardos

Cheng Cheng

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00133a022

1-(2-Deoxy-β-D-ribofuranosyl)-5-(methylmercapto)-2-pyrimidinone (1b) was synthesized via modification of the silyl method. 1b inhibits the Herpes simplex virus type 1 (98%) and type 2 (97%) at a concentration which is nontoxic to human HeLa cells. The com

Full text of DOI:10.1021/jm00133a022

Products guided by the article

Product name:1-(2-deoxy-beta-D-ribofuranosyl)-5-(methylmercapto)-2-pyrimidinone

Cas No:75670-13-2

R&D Labs maybe for 75670-13-2

Shanghai Longschem Co.,Ltd

Contact:021-36356756

Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Taizhou Shengxing Chempharm Co.,Ltd

Contact:+86-576-88516600

Address:Yantou Chemical Zone Jiaojiang Taizhou Zhejiang China
Jinhua City Mingzhu Pharmaceutical Co.,Ltd.

Contact:15857995878 0579-82207761

Address:No.169 Shenze Road, New Area,Jinpan Development Zone, Jinhua
Suzhou Jingye Medicine & Chemical Co., Ltd

website:http://www.jingyechem.cn

Contact:+86-512-66658588

Address:No. 88, Sanlian Street, Jinfeng Road, Suzhou New District, Jiangsu Province, P. R. China
Chengdu Green technology Co.,Ltd.

Contact:86-28-82608355

Address:C9 ,Economic Headquarters, Economic Development Zone, Chengdu.

Relevant to this article

A new phenolic metabolite, involutone, isolated from the mushroom Paxillus involutus

Doi:10.1139/v02-194
(2003)
Palladium/tris(tert-butyl)phosphine-catalyzed Suzuki cross-couplings in the presence of water

Doi:10.1002/adsc.201000267
(2010)
Improved synthetic access to the β,γ-enol ether amino acids, L-2-amino-4-methoxy-trans-but-3-enoic acid and 1-2-amino-4-methoxy-_cis-but-3-enoic acid

Doi:10.1016/S0040-4039(00)98044-4
(1990)
Selective Thromboxane Synthetase Inhibitors. 1. 1-<(Aryloxy)alkyl>-1H-imidazoles

Doi:10.1021/jm00148a009
(1985)
Studies of Bitter Peptides from Casein Hydrolyzate. X. Synthesis and Bitter Taste of H-Arg-Gly-Pro-Phe-Pro-Ile-Ile-Val-OH Corresponding to C-Terminal Portion of &β-Casein

Doi:10.1246/bcsj.57.819
(1984)
Sigmatropic Rearrangements of 1,1-Diarylindenes. Migratory Aptitudes of Aryl Migration in the Ground and Electronically Excited States

Doi:10.1021/jo00318a018
(1981)

Article Doi