Total Synthesis of (-)-Prezizaene and (-)-Prezizanol

Article abstract of DOI:10.1021/jo01314a062

An 18-step total synthesis of the novel zizaane sesquiterpenes, (-)-prezizaene (1) and (-)-prezizanol (2), from (+)-pulegone is described; the key step of the synthesis is the intramolecular ring expansion of (diazoethyl)hydrindanone 12 to the isomeric me