Journal of Pharmaceutical Sciences p. 1044 - 1049 (1980)
Update date:2022-08-04
Topics:
Imakura
Lee
Sims
Wu
Hall
Furukawa
Itoigawa
Yonaha
The antitumor sesquiterpene lactones microhelenine-A, B, and C, microlenin acetate, and plenolin were isolated from Helenium microcephalum. The structures and stereochemistry of these lactones were determined by physical methods as well as by chemical transformations and correlations. Microlenin acetate appears to be the first novel dimeric sesquiterpene lactone demonstrated to have significant antileukemic activity.
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Doi:10.1248/cpb.40.240
(1992)Doi:10.1055/s-1980-29269
(1980)Doi:10.1055/s-0031-1290756
(2012)Doi:10.1021/ja01617a056
(1955)Doi:10.1039/b407468h
(2004)Doi:10.1002/hlca.19800630734
(1980)
