Bioorganic and Medicinal Chemistry Letters p. 4348 - 4351 (2008)
Update date:2022-07-30
Topics:
Sweeney, Zachary K.
Acharya, Sahaja
Briggs, Andrew
Dunn, James P.
Elworthy, Todd R.
Fretland, Jennifer
Giannetti, Anthony M.
Heilek, Gabrielle
Li, Yu
Kaiser, Ann C.
Martin, Michael
Saito, Y. David
Smith, Mark
Suh, Judy M.
Swallow, Steven
Wu, Jeffrey
Hang, Julie Q.
Zhou, Amy S.
Klumpp, Klaus
Novel non-nucleoside inhibitors of HIV-RT that contain pyridazinone isosteres were prepared, and a series of triazolinones were found to be potent inhibitors of HIV replication. These compounds were active against several NNRTI-resistant virus strains. Ph
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