Journal of Organic Chemistry p. 2514 - 2520 (1981)
Update date:2022-09-26
Topics:
Brittelli, David R.
Sequential treatment of a 2-halo carboxylic acid with a dialkyl phosphite and an aldehyde or ketone in the presence of 3 equiv of sodium hydride in glyme constitutes a new general acrylic acid synthesis superior to conventional methods.An alkoxide-in-alcohol variant may be used with bromo- or chloroacetic acid and aryl aldehydes to produce cinnamic acids conveniently.The scope and other features of the synthesis are discussed.
View MoreContact:86+21-56421993
Address:3F,BUILDING 10,NO.2889 JINKE ROAD, SHANGHAI.
Chengdu Better Pharmaceutical Technology Co.,Ltd.
Contact:+86 28 82252524
Address:Tianfu Incubation Park,Hi-tech Zone,Chengdu City, Sichuan Province
Nanjing Zelang Medical Technology Co. Ltd
Contact:86-25-83063290/13770714480
Address:Ganjiabian 108# 01 Unit,701-702 room,Yao Hua Street,Qixia District,Nanjing,Jiangsu,China
website:http://www.alwaychem.com
Contact:+86-532-8586-4000, 8586-5000
Address:NO.51, TAIPING ROAD, QINGDAO, CHINA. 266001
BAODING SINO-CHEM INDUSTRY CO.,LTD
Contact:0312-5956088
Address:NO.8 FUXING ROAD,CHINA
Doi:10.1021/ja046147y
(2004)Doi:10.1016/S0040-4039(01)91407-8
(1984)Doi:10.1002/cjoc.201190223
(2011)Doi:10.1002/ardp.19382760404
(1938)Doi:10.1070/MC2003v013n06ABEH001819
(2003)Doi:10.1039/j39690001858
(1969)
