Journal of Organic Chemistry p. 2514 - 2520 (1981)
Update date:2022-09-26
Topics:
Brittelli, David R.
Sequential treatment of a 2-halo carboxylic acid with a dialkyl phosphite and an aldehyde or ketone in the presence of 3 equiv of sodium hydride in glyme constitutes a new general acrylic acid synthesis superior to conventional methods.An alkoxide-in-alcohol variant may be used with bromo- or chloroacetic acid and aryl aldehydes to produce cinnamic acids conveniently.The scope and other features of the synthesis are discussed.
View Morejintan yufan Medicine Raw materials Co.,Ltd.(expird)
Contact:86-519-82808282
Address:6th,Jincheng Huangzhuang
website:http://www.maisonchem.com.cn
Contact:0086-311-83833777
Address:Leitou industrial district, xinji, shijiazhuang city, hebei province,
Shandong united-rising pharmaceutical cooperation.,ltd.
Contact:008653187965009
Address:171No., Jing5 Road, Shizhong District, Jinan, China
Tianjin Crest Pharmaceutical R&D Co., Ltd. （Tianjin Yao Technology Development Co., Ltd.）(expird)
Contact:+86-22-66211386
Address:Building B5-405, No, 80 4th Avenue, TEDA, Tianjin, China P.R. 300457
Wuhan Shangrisyn chemicals Technology Co.,Ltd(expird)
Contact:+86-027-84466317 __ +86-15387123698
Address:wuhan - china
Doi:10.1021/ja046147y
(2004)Doi:10.1016/S0040-4039(01)91407-8
(1984)Doi:10.1002/cjoc.201190223
(2011)Doi:10.1002/ardp.19382760404
(1938)Doi:10.1070/MC2003v013n06ABEH001819
(2003)Doi:10.1039/j39690001858
(1969)
