Journal of Organic Chemistry p. 2455 - 2465 (1981)
Update date:2022-08-02
Topics:
Barker, Peter L.
Gendler, Paul L.
Rapoport, Henry
The site of acylation in difunctional compounds containing an amine and either an amidine or guanidine can be determined from the ultraviolet absorption spectrum of the acylated product.If the amidine or guanidine has been acylated, the product possesses a chromophore that is pH dependent, whereas if an amide was formed, the chromophore is independent of pH.
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