SYNTHESIS OF AN ISOMER OF THE GERMACRANOLIDE ISOARISTOLACTONE

Article abstract of DOI:10.1016/0040-4039(81)80083-4

Photocycloaddition of (+)-isopiperitenone and cyclobutene-1-carboxylic acid gives an adduct which upon reduction with NaCNBH3 followed by thermolysis yields an isomer of isoaristolactone in an overall yield of 26percent.