Tetrahedron Letters p. 4739 - 4742 (1980)
Update date:2022-08-04
Topics:
Epsztajn, Jan
Berski, Zbigniew
Brzezinski, Jacek Z.
Jozwiak, Andrzej
The behaviour of the N,N-dimethyl-, N,N-diethyl- and N,N,-diisopropylpyridylcarboxylic amides in the reactions with Et2NLi and iPr2NLi, and a convenient way of synthesis of 2,3- and 3,4-disubstituted pyridines, by the direct lithiation of N,N-diisopropylamides leading subsequently to the ortho new C-C bonds formation, are described.
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(2016)