A SHORT SYNTHESIS OF THE Δ1-CARBOPENEM RING SYSTEM

DOI: 10.1016/0040-4039(81)80052-4

Source and publish data:

Tetrahedron Letters p. 191 - 194 (1981)

Update date:2022-08-05

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Authors:

Venugopalan, B.

Hamlet, A. Bevin

Durst, Tony

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Article abstract of DOI:10.1016/0040-4039(81)80052-4

Michael addition of N-lithio-4-vinyl-azetidin-2-one to several vinyl phosphonates gave adducts which were converted to Δ¹-carbopenems via ozonolysis and an intramolecular Horner-Wittig reaction.

Full text of DOI:10.1016/0040-4039(81)80052-4

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