Journal of Organic Chemistry p. 3157 - 3158 (1981)
Update date:2022-08-04
Topics:
Smith, Kirk J.
Bergbreiter, David E.
Newcomb, Martin
Regioselectivity in deprotonation of (Z)-tert-butyl,(Z)-cyclohexyl,(Z)-benzyl,and (Z)-phenyl ketimines of 3-pentanone has been shown to be generally low and variable.Deprotonation of 13CH3-labeled Z ketimines with either lithium diisopropylamide or lithium diethylamide in THF and methylation at -78 deg C was used to determine regiochemistry.Syn/anti deprotonation ratios varied from 74/26 to 22/78 with different ketimines and different bases.
View MoreSEA BRGIHT INDUSTRY CO.,LIMITED
Contact:0086 755 8622 3990
Address:Rm 17B3,GuangCaiXinTianDi Bldg,GuiMiao Rd,NanShan District,Shenzhen,China
UK SHAREPOINT INTERNATIONAL TRADE CO., LTD(expird)
Contact:44-20-31299469
Address:FLAT 107 25 INDESCON SQUARE LONDON UNITED KINGDOM E14 9DG
Binzhou Holly Pharmaceutical Co.,Ltd.
Contact:74517
Address:No.15 Dapu Road,Huangpu District Shanghai,P.R.China
Cerametek Materials（ShenZhen）Co., Ltd.
Contact:+86-755-2324.2554
Address:A3-#9, YongChuan Street, Suite 501
Contact:+86-10-83993285
Address:Rm.1708, Haobai Tower, Building 6, No.50, North Road, West Third Ring, Haidian District, Beijing, China
Doi:10.1021/acs.joc.5b02248
(2016)Doi:10.1007/s11172-017-1856-y
(2017)Doi:10.1021/jm00135a021
(1981)Doi:10.1016/0031-9422(75)80397-9
(1975)Doi:10.1248/cpb.28.2602
(1980)Doi:10.1021/jo00319a046
(1981)
