Synthesis of Spiro as Potential Central Nervous System Agents. 6. Synthesis, 13C NMR, and Biological Evaluation of cis-and trans-4-Amino-3'-arylspiro Derivatives

DOI: 10.1021/jm00137a025

Source and publish data:

Journal of Medicinal Chemistry p. 617 - 621 (1981)

Update date:2022-08-04

Topics:

Authors:

Martin, Lawrence L.

Worm, Manfred

Agnew, Marc N.

Kruse, Hansjoerg

Wilker, Jeffrey C.

Geyer, Harry M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00137a025

4-(Dimethylamino)- and 4-(methylamino)-3'-arylspiro derivatives were prepared as analogues of previously reported 3-arylspiro.Metalation of benzanilide with n-butyllithium, addition

Full text of DOI:10.1021/jm00137a025

Products guided by the article

Product name:4-Dimethylamino-3'-(4-fluoro-phenyl)-3'H-spiro[cyclohexane-1,1'-isobenzofuran]-3'-ol

Cas No:78262-91-6

R&D Labs maybe for 78262-91-6

Suzhou Credit International Trading Co., Ltd

Contact:+86-512-65398039

Address:Qingdeng, Hightech. District, Suzhou
BAODING SINO-CHEM INDUSTRY CO.,LTD

Contact:0312-5956088

Address:NO.8 FUXING ROAD,CHINA
Melone Pharmaceutical Co., ltd

Contact:+86-411 82593920, 82593631

Address:No 232, JInma Roda, Development Zone, Dalian, China
ZhangJiaGang YaRui Chemical Co.,Ltd.

Contact:0512-58360968

Address:China JiangSu Province Zhang Jia Gang City YangShe Oriental Plaza Building 10 B307
Xi'an Herbland Tech Inc.

Contact:+86-29-88710656

Address:South Tai bai Road, High Tech Development Zone, Xi'an China

Relevant to this article

Restricted Internal Rotations in Some Ortho-Substituted Diaryl Sulfides and Sulfones

Doi:10.1021/jo00335a027
(1981)
SYNTHESIS AND STRUCTURE OF PENTACARBONYL(MESITYLDIPHENYLMETHYLENEPHOSPHINE)CHROMIUM(0)

Doi:10.1016/S0022-328X(00)82233-0
(1981)
The formal total synthesis of FR252921-An immunosuppressant

Doi:10.1002/ejoc.201201097
(2013)
Tetranortriterpenoids and Related Compounds. Part 26. Tecleanin, a Possible Precursor of Limonin, and Other New Tetranortriterpenoids from Teclea grandifolia Engl. (Rutaceae)

Doi:10.1039/P19810001750
(1981)
Triorganoantimony(V) carboxylates: Synthesis, characterization and crystal structure of [Me₃Sb(O₂C-C₅H₄N)₂] · H₂O

Doi:10.1016/j.jorganchem.2007.07.033
(2007)
Chemiluminescent acridinium-9-carboxamide boronic acid probes: Application to a homogeneous glycated hemoglobin assay

Doi:10.1016/j.bmcl.2005.11.062
(2006)

Article Doi