Synthesis of Spiro as Potential Central Nervous System Agents. 6. Synthesis, 13C NMR, and Biological Evaluation of cis-and trans-4-Amino-3'-arylspiro Derivatives

DOI: 10.1021/jm00137a025

Source and publish data:

Journal of Medicinal Chemistry p. 617 - 621 (1981)

Update date:2022-08-04

Topics:

Authors:

Martin, Lawrence L.

Worm, Manfred

Agnew, Marc N.

Kruse, Hansjoerg

Wilker, Jeffrey C.

Geyer, Harry M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00137a025

4-(Dimethylamino)- and 4-(methylamino)-3'-arylspiro derivatives were prepared as analogues of previously reported 3-arylspiro.Metalation of benzanilide with n-butyllithium, addition

Full text of DOI:10.1021/jm00137a025

Products guided by the article

Product name:4-Dimethylamino-3'-(4-fluoro-phenyl)-3'H-spiro[cyclohexane-1,1'-isobenzofuran]-3'-ol

Cas No:78262-91-6

R&D Labs maybe for 78262-91-6

Xinxiang Junlong Biological Technology Co., Ltd.

website:https://junlongbio.lookchem.com/

Contact:86-13525059581

Address:Xinxiang City, Henan Province
Hangzhou Taiyan Trading Co., Ltd(expird)

Contact:+86-13777583958

Address:NO.63, Xingyi Street, Xihu District, Hangzhou, Zhejiang, China
SuZhou Hua-Emy Chemical Import and Export Co., LTD.

Contact:+86-512-88804994; +86-512-88804550;

Address:710, Building B, International Trade Center, 12 Huanghelu, Changshu, Jiangsu,China
X.T.Y Environ-Tech Co.,Ltd

Contact:+86-310-7092106

Address:Quzhou Modern & New Industrial Park, Handan, Hebei 057250, China
Qingdao Kylin Trading Co., Ltd.

Contact:0086-532-68979884/58972912/68972263/65/88171519

Address:Room 2308,A building International Trade Center No.230 Changjiang Middle Road of Qingdao Economic Development Zone,Shandong,China.

Relevant to this article

Restricted Internal Rotations in Some Ortho-Substituted Diaryl Sulfides and Sulfones

Doi:10.1021/jo00335a027
(1981)
SYNTHESIS AND STRUCTURE OF PENTACARBONYL(MESITYLDIPHENYLMETHYLENEPHOSPHINE)CHROMIUM(0)

Doi:10.1016/S0022-328X(00)82233-0
(1981)
The formal total synthesis of FR252921-An immunosuppressant

Doi:10.1002/ejoc.201201097
(2013)
Tetranortriterpenoids and Related Compounds. Part 26. Tecleanin, a Possible Precursor of Limonin, and Other New Tetranortriterpenoids from Teclea grandifolia Engl. (Rutaceae)

Doi:10.1039/P19810001750
(1981)
Triorganoantimony(V) carboxylates: Synthesis, characterization and crystal structure of [Me₃Sb(O₂C-C₅H₄N)₂] · H₂O

Doi:10.1016/j.jorganchem.2007.07.033
(2007)
Chemiluminescent acridinium-9-carboxamide boronic acid probes: Application to a homogeneous glycated hemoglobin assay

Doi:10.1016/j.bmcl.2005.11.062
(2006)

Article Doi