Synthesis of Spiro as Potential Central Nervous System Agents. 6. Synthesis, 13C NMR, and Biological Evaluation of cis-and trans-4-Amino-3'-arylspiro Derivatives

DOI: 10.1021/jm00137a025

Source and publish data:

Journal of Medicinal Chemistry p. 617 - 621 (1981)

Update date:2022-08-04

Topics:

Authors:

Martin, Lawrence L.

Worm, Manfred

Agnew, Marc N.

Kruse, Hansjoerg

Wilker, Jeffrey C.

Geyer, Harry M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00137a025

4-(Dimethylamino)- and 4-(methylamino)-3'-arylspiro derivatives were prepared as analogues of previously reported 3-arylspiro.Metalation of benzanilide with n-butyllithium, addition

Full text of DOI:10.1021/jm00137a025

Products guided by the article

Product name:4-Dimethylamino-3'-(4-fluoro-phenyl)-3'H-spiro[cyclohexane-1,1'-isobenzofuran]-3'-ol

Cas No:78262-91-6

R&D Labs maybe for 78262-91-6

SunaTech Inc.

Contact:+86 512 6287 2180

Address:398 Ruoshui Road, Suzhou Industrial Park, Suzhou, Jiangsu, P. R. China
A-Chem Technologies Co.,Ltd.

Contact:+86-512-69561895

Address:No.111, Building A4, 218 Xinghu Street, Suzhou Industrial Park, P. R. China
Xi’an Gaoyuan Bio-Chem Co.,Ltd.

Contact:+86-29-65692259

Address:R11702, Block B, Greenland Soho, 1st Zhangba Rd, Xi'an Hi-tech Zone, Xi'an, Shaanxi, China. 710065
H&Y International Group Ltd

Contact:+86-571-86491666

Address:SHI XIANG ROAD
Hangzhou Ocean Chemical Co., Ltd.

website:http://www.hzoceanchem.com

Contact:+86-571-88025872, 28272092, 28272096

Address:Room 623 ,Building No 1 , COFCO Radius Commercial Center Xiwen Road, Xiacheng District, Hangzhou, Zhejiang Province, China

Relevant to this article

Restricted Internal Rotations in Some Ortho-Substituted Diaryl Sulfides and Sulfones

Doi:10.1021/jo00335a027
(1981)
SYNTHESIS AND STRUCTURE OF PENTACARBONYL(MESITYLDIPHENYLMETHYLENEPHOSPHINE)CHROMIUM(0)

Doi:10.1016/S0022-328X(00)82233-0
(1981)
The formal total synthesis of FR252921-An immunosuppressant

Doi:10.1002/ejoc.201201097
(2013)
Tetranortriterpenoids and Related Compounds. Part 26. Tecleanin, a Possible Precursor of Limonin, and Other New Tetranortriterpenoids from Teclea grandifolia Engl. (Rutaceae)

Doi:10.1039/P19810001750
(1981)
Triorganoantimony(V) carboxylates: Synthesis, characterization and crystal structure of [Me₃Sb(O₂C-C₅H₄N)₂] · H₂O

Doi:10.1016/j.jorganchem.2007.07.033
(2007)
Chemiluminescent acridinium-9-carboxamide boronic acid probes: Application to a homogeneous glycated hemoglobin assay

Doi:10.1016/j.bmcl.2005.11.062
(2006)

Article Doi