Tetrahedron Letters p. 847 - 850 (1981)
Update date:2022-08-02
Topics:
Asseline, U.
Thuong, N. T.
The O,S-dimethylphosphorochloridate 10 reacts with 5'-O-monomethoxytritylthymidine 11 in pyridine giving nucleoside-3'-thiolophosphodiester 13 in high yields ; in acetonitrile and in the presence of 1-methylimidazole, this reaction leads to the nucleoside-3'-phosphotriester 14 without formation of diester 13.From the latter, the Tp and TpT have been prepared.
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(2014)Doi:10.1016/0022-328X(85)80027-9
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(1981)Doi:10.1016/j.ejps.2006.05.010
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(1968)
