Purines. LII. Synthesis and biological evaluation of 8-methylguanine 7-oxide and its 9-arylmethyl derivatives

DOI: 10.1248/cpb.40.1315

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1315 - 1317 (1992)

Update date:2022-08-03

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Authors:

Ogawa Ogawa

Nishii Nishii

Inagaki Inagaki

Nohara Nohara

Saito Saito

Itaya Itaya

Fujii Fujii

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Article abstract of DOI:10.1248/cpb.40.1315

The synthesis of 8-methylguanine 7-oxide (3) was accomplished via a 'phenacylamine route', which started from condensation of α-(4-methoxybenzylamino)propiophenone (6), prepared by coupling of α-bromopropiophenone (4) and 4-methoxybenzylamine (5), with 2-

Full text of DOI:10.1248/cpb.40.1315

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