4-CHLOROPHENYL 5-CHLORO-8-QUINOLYL PHOSPHOROTETRAZOLIDE: A HIGHLY EFFICIENT PHOSPHORYLATING AGENT FOR OLIGORIBONUCLEOTIDE SYNTHESIS

DOI: 10.1246/cl.1981.543

Source and publish data:

Chemistry Letters p. 543 - 546 (1981)

Update date:2022-08-05

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Authors:

Takaku, Hiroshi

Nomoto, Tadaaki

Kamaike, Kazuo

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Article abstract of DOI:10.1246/cl.1981.543

4-Chlorophenyl 5-chloro-8-quinolyl phosphorotetrazolide (2) was a highly efficient phosphorylating agent for the synthesis of 5'-O-dimethoxytrityl-2'-O-tetrahydropyranylnucleoside 3'-(4-chlorophenyl, 5-chloro-8-quinolyl) phosphates (4).The fully protected

Full text of DOI:10.1246/cl.1981.543

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