Organic Letters p. 3853 - 3856 (2004)
Update date:2022-07-29
Topics:
Overman, Larry E.
Velthuisen, Emile J.
12-Oxatricyclo[6.3.1.02,7]dodecanes can be efficiently synthesized in a stereoselective manner by Prins-pinacol reactions. By biasing the transition state of the Prins cyclization, it is possible to access either stereoisomer of this oxatricyclic ring system.
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