PALLADIUM-CATALYZED REGIOSELECTIVE REACTIONS OF α-ACETOXY-β,γ-UNSATURATED NITRILES AND γ-ACETOXY-α,β-UNSATURATED ESTER WITH NUCLEOPHILES

Article abstract of DOI:10.1016/S0040-4039(01)90523-4

α-Acetoxy-β,γ-unsaturated nitriles react at room temperature with malonates and acetoacetates in the presence of palladium-phosphine complexes as a catalyst to give γ-substituted α,β-unsaturated nitriles selectively.Also γ-acetoxy-α,β-unsaturated ester wa