Nucleosides, nucleotides and nucleic acids p. 1249 - 1263 (2005)
Update date:2022-07-29
Hadj-Bouazza, Amel
Zerrouki, Rachida
Krausz, Pierre
Laumond, Geraldine
Aubertin, Anne Marie
Champavier, Yves
The synthesis of new acyclic nucleosides is described. These syntheses were accomplished by various methods: glycosylation, selective or total deprotection, oxidation/reduction, chlorination or azidation of hydroxyl groups. The compounds were characterized with NMR, mass and IR spectroscopy. Antiviral properties of these compounds were evaluated on HIV-1 infected cell lines. Copyright Taylor & Francis, Inc.
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