Tetrahedron Letters p. 4093 - 4096 (1981)
Update date:2022-08-02
Topics:
Akiba, Kin-ya
Matsuoka, Hideto
Wada, Makoto
Regiospecific synthesis of 4-substituted pyridines is attained via alkylation of diisopropyl 1-ethoxycarbonyl-1,4-dihydropyridine-4-phosphonate followed by treatment with butyllithium.The phosphonate is prepared directly from pyridine in one pot.
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Doi:10.1055/s-2004-831229
(2004)Doi:10.1016/j.bmcl.2004.09.004
(2004)Doi:10.1021/jacs.9b07729
(2019)Doi:10.1248/cpb.29.3433
(1981)Doi:10.1016/S0040-4039(01)82962-2
(1981)Doi:10.1016/S0020-1693(00)88578-3
(1981)
