Defined Dimensional Alterations in Enzyme Substrates. Synthesis and Enzymatic Evaluation of Some lin-Naphthopurines

Article abstract of DOI:10.1021/ja00373a046

The development of methodology for the regioselective syntheses of tetra-β-substituted naphthalenes via a combination of bicyclo<4.2.0>octa-1,3,5-triene and aryl trimethylsilyl chemistry led to the synthesis of benzimidazo<5,6-g>-6H,8H-quinazoline-7,9-dio