FORMATION AND REACTIVITY OF DILITHIATED N-FURFURYLBENZAMIDES. SYNTHESIS OF α-SUBSTITUTED N-FURFURYLBENZAMIDES

DOI: 10.1016/S0040-4039(01)93021-7

Source and publish data:

Tetrahedron Letters p. 4487 - 4488 (1981)

Update date:2022-08-06

Topics:

Authors:

Ohno, Kosei

Machida, Minoru

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Article abstract of DOI:10.1016/S0040-4039(01)93021-7

Dianion 3 can be efficiently and regioselectively generated from N-furfurylbenzamide with lithium diisopropylamide/tetrahydrofuran/-78 degC and react with various electrophiles to give α-substituted N-furfurylbenzamide derivatives in good yields.

Full text of DOI:10.1016/S0040-4039(01)93021-7

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