Journal of the Chemical Society. Perkin transactions I p. 3242 - 3249 (1981)
Update date:2022-08-04
Topics: Characterization Purification Final steps Stereochemistry Control Starting Materials Purification and Analysis Ring Expansion Functional Group Manipulations Oxidation and Reduction Further Elaboration
Bateson, John H.
Baxter, Andrew J. G.
Roberts, Patricia M.
Smale, Terence C.
Southgate, Robert
4-Allylazetidin-2-one, prepared from penta-1,4-diene and chlorosulphonyl isocyanate, has been used to synthesise the parent 7-oxo-1-azabicyclo<3.2.0>hept-2-ene-2-carboxylate system of the naturally occurring olivanic acids, using an intramolecular Wittig reaction to construct the 2,3-double bond.Cyclisation of ketones derived from the 4-allyl grouping produced 3-substituted derivatives, while use of the azetidin-2-one prepared from hexa-1,5-diene and chlorosulphonyl isocyanate has given the homologous 8-oxo-1-azabicyclo<4.2.0>oct-2-ene system.
View MoreChongqing maohuan Chemicals Co., Ltd
website:http://www.bschem.com
Contact:+86 13996103726
Address:Chongqing Nan'an District Tu Town
QINGDAO NEW FLOURISH INTERNATIOANAL TRADE CO., LTD.
Contact:+86 532 80861829
Address:No. 1, Yinchuan East Road, 266061, Qingdao, China
Zhuhai Rundu Pharmaceutical co.,Ltd
Contact:+86-756-7630755
Address:No.6,North Airport Road,Sanzao Town,Jinwan District
Chengdu Chengnuo New-Tech Co., Ltd
Contact:0086-028-85749078
Address:4 Jiuyang road,Jiulong industrial port,Chengdu, China
Zhejiang Haizhou Pharmaceutical Co., Ltd.
website:https://www.haizhoupharma.com/
Contact:+86-576-88221016
Address:No. 19, Donghai 5th Avenue, Yanhai Industrial Zone, Linhai, Zhejiang, China
Doi:10.1016/j.carres.2017.10.014
(2017)Doi:10.1039/c3ob26909d
(2013)Doi:10.1246/cl.1982.411
(1982)Doi:10.1016/j.farmac.2004.05.006
(2004)Doi:10.1002/anie.201107490
(2012)Doi:10.1016/S0040-4020(01)90617-9
(1986)
