Tetrahedron Letters p. 4813 - 4814 (1981)
Update date:2022-08-05
Topics:
Godard, A.
Queguiner, G.
The selective reduction of 3,4-dicarbomethoxyquinoline by lithium aluminium hydride at low temperature affords only the unexpected 3-formyl 4-carbomethoxy quinoline.The difficulty of reduction of the usually more reactive 4-ester group can be explained by a steric hindrance by the H5 peri proton on one side and by the 3-ester group on the other side.
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Doi:10.1039/P19820000535
(1982)Doi:10.1021/jo062239p
(2007)Doi:10.1021/jm00349a011
(1982)Doi:10.1016/j.tetlet.2004.10.078
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(1982)
