
Journal of Organic Chemistry p. 2328 - 2331 (1982)
Update date:2022-07-30
Topics:
Kametani, Tetsuji
Huang, Shyh-Pyng
Nakayama, Atsushi
Honda, Toshio
A potential compound, ethyl 6-<(1R*)-1-hydroxyethyl>-3,7-dioxo-1-azabicyclo<3.2.0>heptane-2-carboxylate (18), for the synthesis of thienamycin (1), was stereoselectively prepared by 1,3-dipolar cycloaddition of the nitrone (12) and benzyl crotonate as a key reaction.
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Doi:10.1021/ja01344a059
()Doi:10.1002/chem.201902722
(2019)Doi:10.1007/BF00512951
(1982)Doi:10.1021/ol035630v
(2003)Doi:10.1021/jm020459z
(2003)Doi:10.1039/DT9810002489
(1981)