Pyrimidine Derivatives and Related Compounds. Part 41. Reactions of 1,3,6-Trimethyl-5-nitrouracil and its 6-Bromomethyl Analogue with Amines and Hydrazines. Synthesis of Pyrazolopyrimidine N-Oxides and their Ring Expansion to Pyrimidopyrimid

DOI: 10.1039/P19820000277

Source and publish data:

Journal of the Chemical Society. Perkin transactions I p. 277 - 284 (1982)

Update date:2022-09-26

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Authors:

Hirota, Kosaku

Yamada, Yoshihiro

Asao, Tetsuji

Senda, Shigeo

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Article abstract of DOI:10.1039/P19820000277

Reactions of 1,3,6-trimethyl-5-nitrouracil (1) and 6-bromomethyl-1,3-dimethyl-5-nitrouracil (4) with amines and hydrazines have been studied with the aim of synthesising fused-ring pyrimidines.Treatment of compound (4) with primary amines afforded 2-subst

Full text of DOI:10.1039/P19820000277

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