Absolute stereochemistry and dopaminergic activity of enantiomers of 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine

DOI: 10.1021/jm00348a017

Source and publish data:

Journal of Medicinal Chemistry p. 697 - 703 (1982)

Update date:2022-07-30

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Authors:

Kaiser Kaiser

Dandridge

Garvey Garvey

Hahn Hahn

Sarau Sarau

Setler Setler

Bass Bass

Clardy Clardy

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Article abstract of DOI:10.1021/jm00348a017

Resolution of the unique dopamine receptor agonist 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine (1) was achieved by a stereospecific multistep conversion of the readily separated enantiomers of its O,O,N-trimethylated diffractometric analysi

Full text of DOI:10.1021/jm00348a017

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