Molecular design of biologically active compounds based on platelet activating factor (PAF): 7-Oxabicyclo[2.2.1]heptane system as a strong antagonist of PAF

DOI: 10.1248/cpb.40.2891

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2891 - 2893 (1992)

Update date:2022-08-04

Topics:

Authors:

Kobayashi

Eguchi Eguchi

Sato Sato

Kudo Kudo

Inoue Inoue

Ohno Ohno

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Article abstract of DOI:10.1248/cpb.40.2891

7-Oxabicyclo[2.2.1]heptane system was designed based on the PAF structure. Among four stereoisomers synthesized, the diexo derivative turned out to be a new and strong antagonist of PAF.

Full text of DOI:10.1248/cpb.40.2891

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