Synthesis of Racemic (E)- and (Z)-1-Amino-2-phenylcyclopropanecarboxylic Acid: (E)- and (Z)-"Cyclopropylphenylalanine"

Article abstract of DOI:10.1021/jo00138a014

Both E and Z "cyclopropylogs" of DL-phenylalanine (Δ^E-Phe and Δ^Z-Phe) have been prepared by the cyclopropanation of each 4-benzylidene-2-phenyl-5(4H)-oxazolone isomer with diazomethane to from the three-membered ring.Opening of the o